منابع مشابه
Trimodality bladder preservation therapy for muscle-invasive bladder cancer.
Potentially curative treatments for patients with muscle-invasive bladder cancer (MIBC) are underused, especially in the elderly. Trimodality bladder preservation therapy, which includes a maximally safe transurethral resection of the bladder tumor, followed by concurrent chemoradiation, fulfills this currently unmet need. In multiple prospective clinical trials and large institutional series, ...
متن کاملSystemic Therapy for Invasive Bladder Cancer.
BACKGROUND: Bladder cancer is one of the most common malignancies in Western society. In the United States, approximately 10,000 of these patients present with invasive disease, and more progress from superficial bladder cancer. METHODS: The authors review the literature on systemic treatment for both localized and metastatic bladder cancer, and they include their experience in defining approac...
متن کاملTrimodality Therapy for Bladder Preservation in the Elderly Population with Invasive Bladder Cancer
Bladder cancer is considered as primarily a disease of the elderly, typically aged in their 70s or 80s and often with associated medical comorbidities. Unfortunately, fewer elderly patients receive radical treatment for muscle-invasive bladder cancer (MIBC) that their younger counterparts. Over the last decades, several studies have shown that the use of trimodality therapy consisting of transu...
متن کاملBladder Preservation for Muscle Invasive Bladder Cancer
The standard treatment for muscle invasive bladder cancer (MIBC) has been considered to be radical cystectomy (RC) with pelvic lymphadenectomy. However morbidity and impact on quality of life is significant. Radiotherapy has been used in MIBC patients who choose bladder preservation or who are unfit for RC with comparable outcomes. Evidence from some prospective and large retrospective series s...
متن کاملPatterns of Bladder Preservation Therapy Utilization for Muscle-Invasive Bladder Cancer
Background: Trimodality bladder preservation therapy (BPT) in muscle invasive bladder cancer (MIBC) includes a maximal transurethral resection followed by concurrent chemoradiotherapy as an alternative to radical cystectomy (RC) in appropriately selected patients, or as a treatment option in non-cystectomy candidates. Several chemotherapy regimens can be used in BPT, but little is known about c...
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ژورنال
عنوان ژورنال: Urologic Oncology: Seminars and Original Investigations
سال: 2020
ISSN: 1078-1439
DOI: 10.1016/j.urolonc.2020.10.006